Therapeutic Areas

Home »  Therapeutic Areas

WIDE-RANGING EXPERIENCE IN NUMEROUS THERAPEUTIC AREAS

GreenLight Clinical is the CRO of choice in Ophthalmic and Early-phase Research for sponsors and investigators. We have in-depth experience in numerous therapeutic areas, including Oncology and Neurological diseases.

We provide customised solutions to help bring your drugs, therapies and medical devices to market, with speed and safety in equal measure.

With a demonstrated track record in both established and developing clinical trial markets, our clients have one point of contact and transparency throughout development.

We have our own World Class NATA accredited Central Laboratory.

Ophthalmology

Since our inception, we’ve been driven by a passion for ocular medicine & treatments. We’ve focused on building extraordinary clinical, research & laboratory expertise in the ophthalmology field.

Our significant experience & expertise in ophthalmology studies, combined with our operational capability and compliance with global regulatory bodies, ensures an agile, customised & flexible approach to clients’ needs. This, coupled with our own NATA accredited Central Laboratory’s capability and bench of researchers, accelerates the path to approval process.

We deliver successful outcomes because of our advanced therapy experience and the strategic approach we take to patient recruitment – includes pediatrics, geriatrics & rare diseases. This underpins our collaborative, transparent sponsor & investigator partnership style, alongside our Central Lab services – safety testing, PK/PD, biomarkers & genomic testing.

We’re closely supported by our founder and executive leadership expert, Associate Professor Andrew Chang. We pride ourselves on developing meaningful partnerships with clients to develop potential drugs & devices for all areas of the eye – from the ocular surface to the posterior segment of the eye & all conditions affecting the organ. This includes presbyopia, macular degeneration, retinitis pigmentosa, diabetic retinopathy, glaucoma, & dry eye syndrome.

Indication experience includes:

  • Age-related macular degeneration / genetic macular degeneration
  • Leber’s Congenital Amaurosis
  • Retinitis Pigmentosa
  • Achromatopsia
  • Glaucoma
  • Presbyopia
  • Diabetic Macular Edema
  • Devices

Physician-led Oncology studies and trials providing practical, strategic & educational leadership in partnership with our clients.

Oncology

With a collective experience spanning over a century, our physicians and clinicians are highly adept with proven experience across hematology, oncology drug and bio-clinical development.

Our Central Lab capability, with in-house imaging services, provides an integrated approach with a seamless platform to deliver your study or trial, which may have the most complex nuances, with the expertise & understanding required.

We deliver successful outcomes because of our advanced therapy experience and strategic approach to patient recruitment- includes pediatrics, geriatrics and rare diseases. We expedite the planning & execution of effective studies.  

Closely supported by our Executive Leadership team, we pride ourselves on developing meaningful client partnerships to develop potential drugs & devices.

Indication experience includes:

  • Colorectal Cancer
  • Pancreatic Cancer
  • Solid Tumors – Basket Study
  • Soft Tissue Sarcoma
  • Breast Cancer
  • Gastric Cancer
  • Head & Neck Cancer
  • Leukemia
  • Cervical Cancer
  • Lung Cancer
  • Lymphoma
  • Multiple Myeloma
  • Oesophageal Cancer
  • Ovarian Cancer
  • Paediatric Cancer
  • Brain Cancer
  • Prostate Cancer
  • Renal Cancer
  • Skin Cancer

Leading clinical research in antiviral, antibacterial, antifungal & vaccine trials through a combined physician-led, NATA accredited Central Lab supported approach.

Infectious Diseases

We have comprehensive expertise in designing & conducting global phase I-IV clinical trials in adult & paediatric populations, in both new & re-emerging infectious diseases.

Not only are we proven to help clients achieve their objectives, we also help secure government & non-dilutive funding.

Our Central Laboratory & Clinical Trial Logistics capabilities ensure we successfully manage & deliver valuable investigational products in difficult to access regions. This removes the uncertainty around sample integrity & facilitates speciality testing – including microbiology and virology – to fully support your programs.

Driving successful achievement of trial outcomes by accessing leading research scientists both in-house and in partnership, we pride ourselves on the delivery of high quality study reporting, regulatory interface and the ability to meet tight deadlines and go-to-market plans.

Our commitment to bringing new vaccines and treatments to market is passionately backed by our executive leadership team. We pride ourselves on developing close & meaningful partnerships to bring new products to patients who need them most.

Global Clinical Operations Teams supported by International Regulatory Experts in Neurology/CNS trials.

Neurology / CNS

Our people’s experience in Neurology/CNS spans many years. They’ve been intimately involved in key clinical trials of novel therapies for CNS disorders worldwide.

Our patient-centric, innovative approaches to clinical trial design, investigator interaction & participant support ensure the patient’s quality-of-life is our focus at all times. We also provide meaningful support to their caregivers every step of the way.

We’re experienced in pediatric, young-adult, adult and geriatric populations, including the nuance that comes with different age groups & conditions in CNS trials.

Our Clinical Operations teams have an in-depth knowledge of screening tools & rating scales. They provide oversight for rater services, including subjective assessments, inter-rater reliability & scale validation.

Areas we have experience in, include:

  • Epilepsy
  • Ischaemic Stroke
  • Migraine
  • Multiple Sclerosis
  • Subarachnoid Haemorrhage
  • TTR amyloidosis
  • Alzheimer’s Disease
  • Wilson Disease
  • Huntington Disease
  • Acute Pain
  • Neuropathic pain

GreenLight Clinical has extensive global experience in endocrine/metabolic trials including those in emerging markets, including difficult to recruit populations.

Endocrine and Metabolic

GreenLight Clinical has extensive global experience in endocrine/metabolic trials in both developed and emerging markets, along with difficult-to-recruit populations.

Highly experienced experts lead your trial. They have global trial management backgrounds & hands-on know-how, covering the full spectrum of endocrine & metabolic disorders- including concomitant diseases (obesity, hypertension, & associated co-morbidities).

Our operational staff are supported by our Patient Recruitment & Retention team, specialised in the development and implementation of retention techniques- including support & education, coupled with specific strategies for site issues associated with diabetes & obesity trial management.

Our in-depth experience includes broad compound experiences such as Type 1 and Type 2 diabetes, major obesity programmes, hypercholesterolemia, mixed dyslipidemia and triglyceride.

Some areas we have experience in include:

  • Type 2 Diabetes
  • Lipid Studies
  • Obesity Studies
  • Rare Disease

Full-service capability equipped to manage complex programmes in rare & difficult indications

Rare Disease and Orphan Indication

 

Our experience in rare diseases and orphan indications spans the globe. We’ve executed innovative trials in numerous countries, with patient needs our focus at all times.

Given the difficulty of identifying patient populations, key opinion leaders & principal investigators in rare disease, GreenLight Clinical’s Medical Science Liaison (MSL) team drives these studies.

Fully embedded with the sponsor, a dedicated MSL team leverages your product knowledge and vision, with best-in-class clinical trial intelligence & global medical information services, to engage the most suitable sites & investigators to reach your target population.

Our in-house Biostatistics & Medical Writing teams are at the cutting-edge of trial design, developing innovative approaches to maximise statistical power & enrolment efficiency – ensuring rapid progress towards your goals.

These teams are supported by a strategic, physician-led approach with both pediatric & wider rare-disease experience to ensure the patient needs are considered at all times & programs successfully align with global regulatory requirements.

Some areas we have experience in include:

  • Cushing’s Syndrome
  • Dravet Syndrome
  • Duchenne Muscular Dystrophy
  • Fibrodysplasia
  • Growth Hormone Deficiency
  • Renal Vasculitis
  • Retinitis Pigmentosa
  • Stargardt Disease
  • Retinoblastoma
  • Coloboma
  • Acromegaly

Putting patients physical & psychological well-being at the forefront of all of our Dermatalogical studies.

Dermatology

GreenLight Clinical’s experience in dermatology spans topical, transdermal, intravenous and injection based approaches in both the therapeutic & cosmetic space.

Our footprint in the rapidly growing Asia-Pacific region gives you access to valuable new markets in dermatology. Our global footprint allows you to leverage your results into global opportunities.

With highly capable Clinical Operations teams, backed by our global Regulatory Affairs department, GreenLight Clinical is a trusted partner for Dermatology product development.

Some areas we have experience in include:

  • Acne
  • Rosacea
  • Psoriasis
  • Eczema
  • Atopic Dermatitis
  • Tinea Pedis and Fungal Conditions
  • Impetigo
  • Melanoma

What To Expect

Our in-depth expertise, global footprint and investment in data & technology mean we can provide: